PKIB antibody (AA 1-80)

Catalog No. ABIN7223456

This Rabbit Polyclonal antibody specifically detects PKIB in ELISA, IHC, WB and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for PKIB antibody (AA 1-80) (ABIN7223456)

Target: PKIB (Protein Kinase (CAMP-Dependent, Catalytic) Inhibitor beta (PKIB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKIB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PKIB Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-PKI β Polyclonal Antibody

Specificity: PKI β Polyclonal Antibody detects endogenous levels of PKI β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PKI beta at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PKIB

Target: PKIB (Protein Kinase (CAMP-Dependent, Catalytic) Inhibitor beta (PKIB))

Alternative Name: PKI beta

Background: PKIB, PRKACN2, cAMP-dependent protein kinase inhibitor beta, PKI-betaPKIB (protein kinase (cAMP-dependent, catalytic) inhibitor beta) encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of PKIB may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PKIB.

Gene ID: 5570

UniProt: Q9C010

Pathways: Myometrial Relaxation and Contraction