PPP1R2 antibody

Catalog No. ABIN7223364

This Rabbit Polyclonal antibody specifically detects PPP1R2 in ELISA, WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PPP1R2 antibody (ABIN7223364)

Target: PPP1R2 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 2 (PPP1R2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PPP1R2 Antibody

Purpose: Rabbit Anti-IPP-2 Polyclonal Antibody

Specificity: IPP-2 Polyclonal Antibody detects endogenous levels of IPP-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human IPP-2 around the non-phosphorylation site of S120/S121

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PPP1R2

Target: PPP1R2 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 2 (PPP1R2))

Alternative Name: IPP-2

Background: PPP1R2, IPP2, Protein phosphatase inhibitor 2, IPP-2Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2) binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene.

Molecular Weight: 25kD

Gene ID: 5504

UniProt: P41236

Pathways: PI3K-Akt Signaling, Cellular Glucan Metabolic Process