NEK3 antibody (AA 165-265) (Biotin)

Catalog No. ABIN716533

This Rabbit Polyclonal antibody specifically detects NEK3 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for NEK3 antibody (AA 165-265) (Biotin) (ABIN716533)

Target: NEK3 (NIMA related kinase 3 (NEK3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEK3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NEK3 Antibody (Biotin)

Binding Specificity: AA 165-265

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NEK3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NEK3

Target: NEK3 (NIMA related kinase 3 (NEK3))

Alternative Name: NEK3

Background:

Synonyms: HSPK 36, HSPK36, HSPK-36, NEK3, NEK 3, NEK-3, NEK3_HUMAN, Never in mitosis A-related kinase 3, NIMA never in mitosis gene a related kinase 3, NimA related protein kinase 3, NimA-related protein kinase 3, Serine/threonine protein kinase Nek3, Serine/threonine-protein kinase Nek3.

Background: This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar2009].

Gene ID: 4752