PURB antibody

Catalog No. ABIN7230858

The Rabbit Polyclonal anti-PURB antibody (ABIN7230858) specifically detects PURB in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PURB antibody (ABIN7230858)

Target: PURB (Purine-Rich Element Binding Protein B (PURB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PURB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PURB Antibody

Purpose: Rabbit Anti-PURB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PURB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PURB protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PURB

Target: PURB (Purine-Rich Element Binding Protein B (PURB))

Alternative Name: PURB

Background: Transcriptional activator protein Pur-beta, Purine-rich element-binding protein BPURB (Purine Rich Element Binding Protein B) product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of PURB has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Molecular Weight: 34kD

Gene ID: 5814

UniProt: Q96QR8