R-Spondin 3 antibody

Catalog No. ABIN7231194

The Rabbit Polyclonal anti-R-Spondin 3 antibody (ABIN7231194) specifically detects R-Spondin 3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for R-Spondin 3 antibody (ABIN7231194)

Target: R-Spondin 3 (RSPO3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This R-Spondin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-R-Spondin 3 Antibody

Purpose: Rabbit Anti-RSPO3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RSPO3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RSPO3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for R-Spondin 3

Target: R-Spondin 3 (RSPO3)

Alternative Name: RSPO3

Background: Protein with TSP type-1 repeat, hPWTSR, Roof plate-specific spondin-3, hRspo3, Thrombospondin type-1 domain-containing protein 2RSPO3 belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of RSPO3 with bone mineral density and risk of fracture. RSPO3 may be involved in tumor development.

Molecular Weight: 29kD

Gene ID: 84870

UniProt: Q9BXY4