Radixin antibody (AA 120-200)

Catalog No. ABIN7216754

The Rabbit Polyclonal anti-Radixin antibody is suitable to detect Radixin in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for Radixin antibody (AA 120-200) (ABIN7216754)

Target: Radixin (RDX)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Radixin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Radixin Antibody

Binding Specificity: AA 120-200

Purpose: Rabbit Anti-Radixin Polyclonal Antibody

Specificity: Radixin Polyclonal Antibody detects endogenous levels of Radixin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Radixin at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Radixin

Target: Radixin (RDX)

Alternative Name: Radixin

Background: RDX, RadixinRadixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. RDX has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for RDX.

Molecular Weight: 69kD

Gene ID: 5962

UniProt: P35241

Pathways: Regulation of Actin Filament Polymerization, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome