RGS20 antibody (AA 180-260)

Catalog No. ABIN7231026

This Rabbit Polyclonal antibody specifically detects RGS20 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for RGS20 antibody (AA 180-260) (ABIN7231026)

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RGS20 Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-RGS20 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RGS20 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RGS20 protein at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20

Background: Regulator of G-protein signaling 20, RGS20, Gz-selective GTPase-activating protein, Gz-GAP, Regulator of G-protein signaling Z1, Regulator of Gz-selective protein signaling 1The protein encoded by RGS20 (Regulator Of G Protein Signaling 20) belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for RGS20.

Molecular Weight: 42kD

Gene ID: 8601

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling