RTN4R antibody (AA 270-350)

Catalog No. ABIN7231208

The Rabbit Polyclonal anti-RTN4R antibody is suitable to detect RTN4R in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for RTN4R antibody (AA 270-350) (ABIN7231208)

Target: RTN4R (Reticulon 4 Receptor (RTN4R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTN4R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RTN4R Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-RTN4R Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RTN4R protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RTN4R protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RTN4R

Target: RTN4R (Reticulon 4 Receptor (RTN4R))

Alternative Name: RTN4R

Background: Reticulon-4 receptor, Nogo receptor, NgR, Nogo-66 receptorRTN4R encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Molecular Weight: 52kD

Gene ID: 65078

UniProt: Q9BZR6

Pathways: Neurotrophin Signaling Pathway