ARHGEF10 antibody (AA 310-390)

Catalog No. ABIN7213664

The Rabbit Polyclonal anti-ARHGEF10 antibody is suitable to detect ARHGEF10 in samples from Human and Monkey. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for ARHGEF10 antibody (AA 310-390) (ABIN7213664)

Target: ARHGEF10 (rho Guanine Nucleotide Exchange Factor (GEF) 10 (ARHGEF10))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ARHGEF10 Antibody

Binding Specificity: AA 310-390

Purpose: Rabbit Anti-ARHGEF10 Polyclonal Antibody

Specificity: ARHGEF10 Polyclonal Antibody detects endogenous levels of ARHGEF10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ARHGEF10 at AA range: 310-390

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ARHGEF10

Target: ARHGEF10 (rho Guanine Nucleotide Exchange Factor (GEF) 10 (ARHGEF10))

Alternative Name: ARHGEF10

Background: ARHGEF10, KIAA0294, Rho guanine nucleotide exchange factor 10ARHGEF10 encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in ARHGEF10 are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.

Molecular Weight: 152kD

Gene ID: 9639

UniProt: O15013