ARHGEF4 antibody (AA 270-350)

Catalog No. ABIN7227360

This Rabbit Polyclonal antibody specifically detects ARHGEF4 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ARHGEF4 antibody (AA 270-350) (ABIN7227360)

Target: ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ARHGEF4 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-ARHG4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ARHG4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ARHG4 protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ARHGEF4

Target: ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))

Alternative Name: ARHG4

Background: Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1, Asef, Asef1Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by ARHGEF4 (Rho Guanine Nucleotide Exchange Factor 4) may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined.

Molecular Weight: 75kD

Gene ID: 50649

UniProt: Q9NR80

Pathways: Neurotrophin Signaling Pathway