RRN3 antibody (pSer649)

Catalog No. ABIN7223310

The Rabbit Polyclonal anti-RRN3 antibody (ABIN7223310) specifically detects RRN3 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RRN3 antibody (pSer649) (ABIN7223310)

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RRN3 Antibody

Binding Specificity: pSer649

Purpose: Rabbit Anti-Rrn3 (phospho Ser649) Polyclonal Antibody

Specificity: Phospho-Rrn3 (S649) Polyclonal Antibody detects endogenous levels of Rrn3 protein only when phosphorylated at S649.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Rrn3 Phospho-Ser649

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Alternative Name: Rrn3

Background: RRN3, TIFIA, RNA polymerase I-specific transcription initiation factor RRN3, Transcription initiation factor IA, TIF-IARRN3 (RRN3 Homolog, RNA Polymerase I Transcription Factor) is a Protein Coding gene. Among its related pathways are Gene Expression and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include binding and RNA polymerase binding.

Molecular Weight: 70kD

Gene ID: 54700

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling