RRN3 antibody

Catalog No. ABIN7231806

The Rabbit Polyclonal anti-RRN3 antibody is suitable to detect RRN3 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for RRN3 antibody (ABIN7231806)

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RRN3 Antibody

Purpose: Rabbit Anti-TIF-IA Polyclonal Antibody

Specificity: This antibody detects endogenous levels of TIF-IA.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TIF-IA protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Alternative Name: TIF-IA

Background: RNA polymerase I-specific transcription initiation factor RRN3, Transcription initiation factor IA, TIF-IARRN3 (RRN3 Homolog, RNA Polymerase I Transcription Factor) is a Protein Coding gene. Among its related pathways are RNA Polymerase I Promoter Escape and Gene Expression. Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction

Molecular Weight: 70kD

Gene ID: 54700

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling