Septin 4 antibody

Catalog No. ABIN7231312

This Rabbit Polyclonal antibody specifically detects Septin 4 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Septin 4 antibody (ABIN7231312)

Target: Septin 4 (SEPT4)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Septin 4 Antibody

Purpose: Rabbit Anti-SEPT4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SEPT4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SEPT4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Septin 4

Target: Septin 4 (SEPT4)

Alternative Name: SEPT4

Background: Septin-4, Apoptosis-related protein in the TGF-beta signaling pathway, ARTS, Bradeion beta, Brain protein H5, CE5B3 beta, Cell division control-related protein 2, hCDCREL-2, Cerebral protein 7, Peanut-like protein 2SEPT4 gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct, it is localized to the mitochondria, and has a role in apoptosis and cancer.

Molecular Weight: 52kD

Gene ID: 5414

UniProt: O43236