Septin 5 antibody (AA 180-260)

Catalog No. ABIN7223244

The Rabbit Polyclonal anti-Septin 5 antibody has been validated for WB and ELISA. It is suitable to detect Septin 5 in samples from Human, Rat and Mouse.

Quick Overview for Septin 5 antibody (AA 180-260) (ABIN7223244)

Target: Septin 5 (SEPT5)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Septin 5 Antibody

Binding Specificity: AA 180-260

Purpose: Septin 5 Polyclonal Antibody

Specificity: Septin 5 Polyclonal Antibody detects endogenous levels of Septin 5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Septin 5 at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Septin 5

Target: Septin 5 (SEPT5)

Alternative Name: Septin 5

Background: Rabbit Anti-Septin 5 Polyclonal Antibody,SEPT5, PNUTL1, Septin-5, Cell division control-related protein 1, CDCrel-1, Peanut-like protein 1,SEPT5 (septin 5) is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. SEPT5 is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and SEPT5 has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.,Septin-5

Molecular Weight: observerd band 42kDa

Gene ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis