STK36 antibody (AA 360-440)

Catalog No. ABIN7221112

The Rabbit Polyclonal anti-STK36 antibody (ABIN7221112) specifically detects STK36 in WB, IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for STK36 antibody (AA 360-440) (ABIN7221112)

Target: STK36 (serine/threonine Kinase 36 (STK36))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK36 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-STK36 Antibody

Binding Specificity: AA 360-440

Purpose: Rabbit Anti-STK36 Polyclonal Antibody

Specificity: STK36 Polyclonal Antibody detects endogenous levels of STK36 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human STK36 at AA range: 360-440

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for STK36

Target: STK36 (serine/threonine Kinase 36 (STK36))

Alternative Name: STK36

Background: STK36, KIAA1278, Serine/threonine-protein kinase 36, Fused homologSTK36 encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that STK36 is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 170kD

Gene ID: 27148

UniProt: Q9NRP7