Serotonin Receptor 1A antibody (AA 260-340)

Catalog No. ABIN7217096

This Rabbit Polyclonal antibody specifically detects Serotonin Receptor 1A in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Serotonin Receptor 1A antibody (AA 260-340) (ABIN7217096)

Target: Serotonin Receptor 1A (HTR1A)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Serotonin Receptor 1A Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-SR-1A Polyclonal Antibody

Specificity: SR-1A Polyclonal Antibody detects endogenous levels of SR-1A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human SR-1A at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Serotonin Receptor 1A

Target: Serotonin Receptor 1A (HTR1A)

Alternative Name: SR-1A

Background: HTR1A, ADRB2RL1, ADRBRL1, 5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, G-21, Serotonin receptor 1AHTR1A encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers.

Molecular Weight: 46kD

Gene ID: 3350

UniProt: P08908

Pathways: JAK-STAT Signaling, Synaptic Membrane, Feeding Behaviour