Serotonin Receptor 3A antibody (AA 130-210)
Quick Overview for Serotonin Receptor 3A antibody (AA 130-210) (ABIN7217104)
Target
See all Serotonin Receptor 3A (HTR3A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 130-210
-
Purpose
- SR-3A Polyclonal Antibody
-
Specificity
- SR-3A Polyclonal Antibody detects endogenous levels of SR-3A protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Immunogen
- Synthesized peptide derived from the Internal region of human SR-3A at AA range: 130-210
-
Isotype
- IgG
-
-
-
-
Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
-
Comment
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Serotonin Receptor 3A (HTR3A)
-
Alternative Name
- SR-3A
-
Background
- Rabbit Anti-SR-3A Polyclonal Antibody,HTR3A, 5HT3R, HTR3, 5-hydroxytryptamine receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3R, Serotonin receptor 3A, Serotonin-gated ion channel receptor,The product of HTR3A belongs to the ligand-gated ion channel receptor superfamily. HTR3A encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.,5-hydroxytryptamine receptor 3A
-
Molecular Weight
- observerd band 55kDa
-
Gene ID
- 3359
-
UniProt
- P46098
-
Pathways
- Synaptic Membrane
Target
-