Serotonin Receptor 6 antibody (AA 190-270)

Catalog No. ABIN7221626

This Rabbit Polyclonal antibody specifically detects Serotonin Receptor 6 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Serotonin Receptor 6 antibody (AA 190-270) (ABIN7221626)

Target: Serotonin Receptor 6 (HTR6)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Serotonin Receptor 6 Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-SR-6 Polyclonal Antibody

Specificity: SR-6 Polyclonal Antibody detects endogenous levels of SR-6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human SR-6 at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Serotonin Receptor 6

Target: Serotonin Receptor 6 (HTR6)

Alternative Name: SR-6

Background: HTR6, 5-hydroxytryptamine receptor 6, 5-HT-6, 5-HT6, Serotonin receptor 6HTR6 encodes 5-hydroxytryptamine receptor 6 that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor.

Molecular Weight: 47kD

Gene ID: 3362

UniProt: P50406

Pathways: JAK-STAT Signaling