SIX3 antibody

Catalog No. ABIN7231372

The Rabbit Polyclonal anti-SIX3 antibody (ABIN7231372) specifically detects SIX3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for SIX3 antibody (ABIN7231372)

Target: SIX3 (Sine Oculis-Related Homeobox 3 (SIX3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIX3 Antibody

Purpose: Rabbit Anti-SIX3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SIX3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SIX3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SIX3

Target: SIX3 (Sine Oculis-Related Homeobox 3 (SIX3))

Alternative Name: SIX3

Background: Homeobox protein SIX3, Sine oculis homeobox homolog 3SIX3 (SIX Homeobox 3) is a Protein Coding gene. Diseases associated with SIX3 include Schizencephaly and Holoprosencephaly 2. Among its related pathways are Circadian rythm related genes and Transcriptional Regulatory Network in Embryonic Stem Cell. GO annotations related to SIX3 include transcription factor activity, sequence-specific DNA binding and transcription coactivator activity. An important paralog of SIX3 is SIX6. SIX3 encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in SIX3 have been associated with holoprosencephaly type 2.

Molecular Weight: 36kD

Gene ID: 6496

UniProt: O95343

Pathways: Protein targeting to Nucleus