SLC26A3 antibody (AA 100-180)

Catalog No. ABIN7228292

The Rabbit Polyclonal anti-SLC26A3 antibody (ABIN7228292) specifically detects SLC26A3 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for SLC26A3 antibody (AA 100-180) (ABIN7228292)

Target: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC26A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLC26A3 Antibody

Binding Specificity: AA 100-180

Purpose: Rabbit Anti-DRA Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DRA protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DRA protein at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLC26A3

Target: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Alternative Name: DRA

Background: HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRAHLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

Molecular Weight: 27kD

Gene ID: 3122

UniProt: P01903