SOX12 antibody (AA 40-120)

Catalog No. ABIN7224430

The Rabbit Polyclonal anti-SOX12 antibody is suitable to detect SOX12 in samples from Human and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for SOX12 antibody (AA 40-120) (ABIN7224430)

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX12 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SOX12 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-Sox-12 Polyclonal Antibody

Specificity: Sox-12 Polyclonal Antibody detects endogenous levels of Sox-12 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Sox-12 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SOX12

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Alternative Name: Sox-12

Background: SOX12, SOX22, Transcription factor SOX-12, Protein SOX-22Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by SOX12 (SRY-box 12) was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.

Gene ID: 6666

UniProt: O15370