Stanniocalcin 2 antibody (AA 170-250)

Catalog No. ABIN7231560

This anti-Stanniocalcin 2 antibody is a Rabbit Polyclonal antibody detecting Stanniocalcin 2 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Stanniocalcin 2 antibody (AA 170-250) (ABIN7231560)

Target: Stanniocalcin 2 (STC2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stanniocalcin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Stanniocalcin 2 Antibody

Binding Specificity: AA 170-250

Purpose: STC2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of STC2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human STC2 protein at AA range: 170-250

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Stanniocalcin 2

Target: Stanniocalcin 2 (STC2)

Alternative Name: STC2

Background: Rabbit Anti-STC2 Polyclonal Antibody,Stanniocalcin-related protein, STC-related protein, STCRP,STC2 encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of STC2 is induced by estrogen and altered in some breast cancers.,STC2

Molecular Weight: observerd band 33kDa

Gene ID: 8614

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome