SOCS4 antibody

Catalog No. ABIN7231438

The Rabbit Polyclonal anti-SOCS4 antibody is suitable to detect SOCS4 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for SOCS4 antibody (ABIN7231438)

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SOCS4 Antibody

Purpose: Rabbit Anti-SOCS4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SOCS4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SOCS4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SOCS4

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Alternative Name: SOCS4

Background: Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7The protein encoded by SOCS4 (Suppressor Of Cytokine Signaling 4) contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for SOCS4.

Molecular Weight: 48kD

Gene ID: 122809

UniProt: Q8WXH5

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway