beta Synuclein antibody (AA 60-140)

Catalog No. ABIN7217194

The Rabbit Polyclonal anti-beta Synuclein antibody is suitable to detect beta Synuclein in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for beta Synuclein antibody (AA 60-140) (ABIN7217194)

Target: beta Synuclein (SNCB) (Synuclein, beta (SNCB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Synuclein antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-beta Synuclein Antibody

Binding Specificity: AA 60-140

Purpose: Rabbit Anti-Synuclein-β Polyclonal Antibody

Specificity: Synuclein-β Polyclonal Antibody detects endogenous levels of Synuclein-β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Synuclein-beta at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for beta Synuclein

Target: beta Synuclein (SNCB) (Synuclein, beta (SNCB))

Alternative Name: Synuclein-beta

Background: SNCB, Beta-synucleinSNCB encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The Beta-synuclein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants.

Molecular Weight: 14kD

Gene ID: 6620

UniProt: Q16143