T-Box 18 antibody (AA 90-170)

Catalog No. ABIN7225818

This Rabbit Polyclonal antibody specifically detects T-Box 18 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for T-Box 18 antibody (AA 90-170) (ABIN7225818)

Target: T-Box 18 (TBX18)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 18 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-T-Box 18 Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-TBX18 Polyclonal Antibody

Specificity: TBX18 Polyclonal Antibody detects endogenous levels of TBX18 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TBX18 at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for T-Box 18

Target: T-Box 18 (TBX18)

Alternative Name: TBX18

Background: TBX18, T-box transcription factor TBX18, T-box protein 18TBX18 (T-box 18)codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors.

Molecular Weight: 68kD

Gene ID: 9096

UniProt: O95935

Pathways: Sensory Perception of Sound