TBX2 antibody (AA 220-300)

Catalog No. ABIN7217248

The Rabbit Polyclonal anti-TBX2 antibody is suitable to detect TBX2 in samples from Human and Mouse. It has been validated for ELISA, WB, IHC and IF.

Quick Overview for TBX2 antibody (AA 220-300) (ABIN7217248)

Target: TBX2 (T-Box 2 (TBX2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TBX2 Antibody

Binding Specificity: AA 220-300

Purpose: Rabbit Anti-TBX2 Polyclonal Antibody

Specificity: TBX2 Polyclonal Antibody detects endogenous levels of TBX2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TBX2 at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TBX2

Target: TBX2 (T-Box 2 (TBX2))

Alternative Name: TBX2

Background: TBX2, T-box transcription factor TBX2, T-box protein 2TBX2 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.

Molecular Weight: 74kD

Gene ID: 6909

UniProt: Q13207

Pathways: p53 Signaling