TLX3 antibody

Catalog No. ABIN7231834

The Rabbit Polyclonal anti-TLX3 antibody is suitable to detect TLX3 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for TLX3 antibody (ABIN7231834)

Target: TLX3 (T-Cell Leukemia Homeobox 3 (TLX3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TLX3 Antibody

Purpose: Rabbit Anti-TLX3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TLX3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TLX3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TLX3

Target: TLX3 (T-Cell Leukemia Homeobox 3 (TLX3))

Alternative Name: TLX3

Background: T-cell leukemia homeobox protein 3, Homeobox protein Hox-11L2TLX3 (T-Cell Leukemia Homeobox 3) is a Protein Coding gene. Diseases associated with TLX3 include Precursor T-Cell Acute Lymphoblastic Leukemia and T-Cell Leukemia. Among its related pathways are Transcriptional misregulation in cancer and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The protein encoded by TLX3 is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5,14)(q35,q32)] involving TLX3 is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults.

Molecular Weight: 32kD

Gene ID: 30012

UniProt: O43711