TBXAS1 antibody (C-Term)

Catalog No. ABIN7224614

The Rabbit Polyclonal anti-TBXAS1 antibody (ABIN7224614) specifically detects TBXAS1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TBXAS1 antibody (C-Term) (ABIN7224614)

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXAS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TBXAS1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-TXA synthase Polyclonal Antibody

Specificity: TXA synthase Polyclonal Antibody detects endogenous levels of TXA synthase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human TXA synthase

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TBXAS1

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Alternative Name: TXA synthase

Background: TBXAS1, CYP5, CYP5A1, Thromboxane-A synthase, TXA synthase, TXS, Cytochrome P450 5A1TBXAS1 (thromboxane A synthase 1) encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for TBXAS1.

Molecular Weight: 60kD

Gene ID: 6916

UniProt: P24557