TK1 antibody (pSer13)

Catalog No. ABIN7224708

This Rabbit Polyclonal antibody specifically detects TK1 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse, Rat and Pig.

Quick Overview for TK1 antibody (pSer13) (ABIN7224708)

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TK1 Antibody

Binding Specificity: pSer13

Purpose: Rabbit Anti-Thymidine Kinase (phospho Ser13) Polyclonal Antibody

Specificity: Phospho-Thymidine Kinase (S13) Polyclonal Antibody detects endogenous levels of Thymidine Kinase protein only when phosphorylated at S13.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Thymidine Kinase Phospho-Ser13

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TK1

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Alternative Name: Thymidine Kinase

Background: TK1, Thymidine kinase, cytosolicTK1 (Thymidine kinase, cytosolic) belongs to the thymidine kinase family and is a regulatory enzyme that can interchange between its dimeric and tetrameric forms, which have low and high catalytic efficiencies, respectively. TK1 is involved in DNA synthesis and an important proliferation marker (PMID: 21178264).

Molecular Weight: 25kD

Gene ID: 7083

UniProt: P04183