TTF2 antibody

Catalog No. ABIN7231960

The Rabbit Polyclonal anti-TTF2 antibody is suitable to detect TTF2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for TTF2 antibody (ABIN7231960)

Target: TTF2 (Transcription Termination Factor, RNA Polymerase II (TTF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TTF2 Antibody

Purpose: Rabbit Anti-TTF2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TTF2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TTF2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TTF2

Target: TTF2 (Transcription Termination Factor, RNA Polymerase II (TTF2))

Alternative Name: TTF2

Background: Transcription termination factor 2, Lodestar homolog, RNA polymerase II termination factor, Transcription release factor 2, F2, HuF2TTF2 (Transcription Termination Factor 2) is a Protein Coding gene. Among its related pathways are Insulin secretion and Human Thyroid Stimulating Hormone (TSH) signaling pathway. TTF2 encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.

Molecular Weight: 127kD

Gene ID: 8458

UniProt: Q9UNY4

Pathways: Thyroid Hormone Synthesis