TTF2 antibody

Catalog No. ABIN7467656

The Rabbit Polyclonal anti-TTF2 antibody (ABIN7467656) specifically detects TTF2 in WB, IF, ICC, IP and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TTF2 antibody (ABIN7467656)

Target: TTF2 (Transcription Termination Factor, RNA Polymerase II (TTF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TTF2 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TTF2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.93 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TTF2

Target: TTF2 (Transcription Termination Factor, RNA Polymerase II (TTF2))

Alternative Name: transcription termination factor 2

Background: Transcription termination factor 2 , HuF2 , ZGRF6,This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq]

Molecular Weight: 130 kDa

Gene ID: 8458

UniProt: Q9UNY4

Pathways: Thyroid Hormone Synthesis