TMEM201 antibody

Catalog No. ABIN7229128

This Rabbit Polyclonal antibody specifically detects TMEM201 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TMEM201 antibody (ABIN7229128)

Target: TMEM201 (Transmembrane Protein 201 (TMEM201))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM201 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TMEM201 Antibody

Purpose: Rabbit Anti-IMA1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IMA1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IMA1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TMEM201

Target: TMEM201 (Transmembrane Protein 201 (TMEM201))

Alternative Name: IMA1

Background: Importin subunit alpha-5, Karyopherin subunit alpha-1, Nucleoprotein interactor 1, NPI-1, RAG cohort protein 2, SRP1-betaKPNA1 (Karyopherin Subunit Alpha 1) is a Protein Coding gene. Diseases associated with KPNA1 include Influenza and Ovarian Endodermal Sinus Tumor. Among its related pathways are HIV Life Cycle and Apoptosis induced DNA fragmentation. The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by KPNA1 belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase.

Molecular Weight: 59kD

Gene ID: 3836

UniProt: P52294