TSC22D3 antibody

Catalog No. ABIN7231644

The Rabbit Polyclonal anti-TSC22D3 antibody (ABIN7231644) specifically detects TSC22D3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TSC22D3 antibody (ABIN7231644)

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC22D3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TSC22D3 Antibody

Purpose: Rabbit Anti-T22D3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of T22D3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human T22D3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TSC22D3

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Alternative Name: T22D3

Background: TSC22 domain family protein 3, DSIP-immunoreactive peptide, Protein DIP, hDIP, Delta sleep-inducing peptide immunoreactor, Glucocorticoid-induced leucine zipper protein, GILZ, TSC-22-like protein, TSC-22-related protein, TSC-22RTSC22D3 encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κ,B. Alternate splicing results in multiple transcript variants.

Molecular Weight: 14kD

Gene ID: 1831

UniProt: Q99576