USP37 antibody

Catalog No. ABIN7232016

The Rabbit Polyclonal anti-USP37 antibody has been validated for ELISA and WB. It is suitable to detect USP37 in samples from Human.

Quick Overview for USP37 antibody (ABIN7232016)

Target: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP37 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-USP37 Antibody

Purpose: UBP37 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of UBP37 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human UBP37 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for USP37

Target: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Alternative Name: UBP37

Background: Rabbit Anti-UBP37 Polyclonal Antibody,Ubiquitin carboxyl-terminal hydrolase 37, Deubiquitinating enzyme 37, Ubiquitin thioesterase 37, Ubiquitin-specific-processing protease 37,USP37 (Ubiquitin Specific Peptidase 37) is a Protein Coding gene. Among its related pathways are Deubiquitination and Ubiquitin-Proteasome Dependent Proteolysis. Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of Lys-11-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of Lys-48-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1.,UBP37

Molecular Weight: observerd band 107kDa

Gene ID: 57695

UniProt: Q86T82