ULK2 antibody (AA 930-1000)

Catalog No. ABIN7226932

This Rabbit Polyclonal antibody specifically detects ULK2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ULK2 antibody (AA 930-1000) (ABIN7226932)

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ULK2 Antibody

Binding Specificity: AA 930-1000

Purpose: Rabbit Anti-ULK2 Polyclonal Antibody

Specificity: The antibody detects endogenous ULK2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 930-1000

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ULK2

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Alternative Name: ULK2

Background: ULK2, KIAA0623ULK2 (unc-51 like autophagy activating kinase 2) encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. ULK2 is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified.

Molecular Weight: 140kD

Gene ID: 9706

UniProt: Q8IYT8

Pathways: Regulation of Cell Size, Autophagy