URI1 antibody (AA 390-470)

Catalog No. ABIN7225638

This Rabbit Polyclonal antibody specifically detects URI1 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for URI1 antibody (AA 390-470) (ABIN7225638)

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This URI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-URI1 Antibody

Binding Specificity: AA 390-470

Purpose: Rabbit Anti-RMP Polyclonal Antibody

Specificity: RMP Polyclonal Antibody detects endogenous levels of RMP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human RMP at AA range: 390-470

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Alternative Name: RMP

Background: URI1, C19orf2, NNX3, PPP1R19, RMP, URI, Unconventional prefoldin RPB5 interactor 1, Protein NNX3, Protein phosphatase 1 regulatory subunit 19, RNA polymerase II subunit 5-mediating protein, RPB5-mediating proteinURI1 (URI1, prefoldin like chaperone) encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. URI1 may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for URI1, and a pseudogene of this gene is located on the long arm of chromosome 22.

Molecular Weight: 56kD

Gene ID: 8725

UniProt: O94763