Vitronectin antibody (Internal Region)

Catalog No. ABIN7224936

The Rabbit Polyclonal anti-Vitronectin antibody is suitable to detect Vitronectin in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Vitronectin antibody (Internal Region) (ABIN7224936)

Target: Vitronectin (VTN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Vitronectin Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Vitronectin Polyclonal Antibody

Specificity: Vitronectin Polyclonal Antibody detects endogenous levels of Vitronectin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Vitronectin

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: Vitronectin

Background: VTN, Vitronectin, VN, S-protein, Serum-spreading factor, V75The protein encoded by VTN (vitronectin) is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Molecular Weight: 55kD

Gene ID: 7448

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration