VDAC3 antibody

Catalog No. ABIN7232082

The Rabbit Polyclonal anti-VDAC3 antibody is suitable to detect VDAC3 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for VDAC3 antibody (ABIN7232082)

Target: VDAC3 (Voltage-Dependent Anion Channel 3 (VDAC3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VDAC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VDAC3 Antibody

Purpose: Rabbit Anti-VDAC3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of VDAC3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human VDAC3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for VDAC3

Target: VDAC3 (Voltage-Dependent Anion Channel 3 (VDAC3))

Alternative Name: VDAC3

Background: Voltage-dependent anion-selective channel protein 3, VDAC-3, hVDAC3, Outer mitochondrial membrane protein porin 3VDAC3 (Voltage Dependent Anion Channel 3) is a Protein Coding gene. Among its related pathways are Calcium signaling pathway and Deubiquitination. VDAC3 encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for VDAC3.

Molecular Weight: 31kD

Gene ID: 7419

UniProt: Q9Y277