WIPF1 antibody (AA 390-470)

Catalog No. ABIN7224938

This anti-WIPF1 antibody is a Rabbit Polyclonal antibody detecting WIPF1 in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for WIPF1 antibody (AA 390-470) (ABIN7224938)

Target: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-WIPF1 Antibody

Binding Specificity: AA 390-470

Purpose: WIP Polyclonal Antibody

Specificity: WIP Polyclonal Antibody detects endogenous levels of WIP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human WIP at AA range: 390-470

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for WIPF1

Target: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Alternative Name: WIP

Background: Rabbit Anti-WIP Polyclonal Antibody,WIPF1, WASPIP, WIP, WAS/WASL-interacting protein family member 1, Protein PRPL-2, Wiskott-Aldrich syndrome protein-interacting protein, WASP-interacting protein,WIPF1 (WAS/WASL interacting protein family member 1) encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for WIPF1.,WAS

Molecular Weight: observerd band 52kDa

Gene ID: 7456

UniProt: O43516

Pathways: RTK Signaling