XRCC4 antibody

Catalog No. ABIN7211178

The Mouse Monoclonal anti-XRCC4 antibody has been validated for WB, IF, IP and IHC (p). It is suitable to detect XRCC4 in samples from Human.

Quick Overview for XRCC4 antibody (ABIN7211178)

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XRCC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-XRCC4 Antibody

Purpose: XRCC4 Monoclonal Antibody

Specificity: The antibody detects endogenous XRCC4 proteins.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

Immunogen: Synthetic Peptide

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:2000), IF (1:100-1:200), IHC-P (1:50-1:300), IP (1:200).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for XRCC4

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Alternative Name: XRCC4

Background: Mouse Anti-XRCC4 Monoclonal Antibody,XRCC4, DNA repair protein XRCC4, X-ray repair cross-complementing protein 4,X-ray repair cross complementing 4 encoded by XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. X-ray repair cross complementing 4 plays a role in both non-homologous end joining and the completion of V (D)J recombination. Mutations in XRCC4 can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.,DNA repair protein XRCC4

Gene ID: 7518

UniProt: Q13426

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response