XPA antibody (AA 180-260)

Catalog No. ABIN7217514

This Rabbit Polyclonal antibody specifically detects XPA in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for XPA antibody (AA 180-260) (ABIN7217514)

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-XPA Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-XPA Polyclonal Antibody

Specificity: XPA Polyclonal Antibody detects endogenous levels of XPA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human XPA at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Alternative Name: XPA

Background: XPA, XPAC, DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing proteinXPA encodes a zinc finger protein involved in DNA excision repair. The DNA repair protein complementing XP-A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 40kD

Gene ID: 7507

UniProt: P23025

Pathways: DNA Damage Repair