ZNRF1 antibody

Catalog No. ABIN7232242

The Rabbit Polyclonal anti-ZNRF1 antibody is suitable to detect ZNRF1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for ZNRF1 antibody (ABIN7232242)

Target: ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ZNRF1 Antibody

Purpose: Rabbit Anti-ZNRF1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ZNRF1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ZNRF1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ZNRF1

Target: ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))

Alternative Name: ZNRF1

Background: E3 ubiquitin-protein ligase ZNRF1, Nerve injury-induced gene 283 protein, RING-type E3 ubiquitin transferase ZNRF1, Zinc/RING finger protein 1ZNRF1 encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons. ZNRF1 (Zinc And Ring Finger 1) is a Protein Coding gene. Diseases associated with ZNRF1 include B-Cell Adult Acute Lymphocytic Leukemia. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System.

Molecular Weight: 24kD

Gene ID: 84937

UniProt: Q8ND25