C-JUN antibody (pSer79)

Catalog No. ABIN7232967

The Rabbit Polyclonal anti-C-JUN antibody (ABIN7232967) specifically detects C-JUN in IHC and IF. The antibody is reactive with Human samples.

Quick Overview for C-JUN antibody (pSer79) (ABIN7232967)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C-JUN antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-C-JUN Antibody

Binding Specificity: pSer79

Purpose: Anti-c-Jun (Phospho-Ser79) Rabbit Polyclonal Antibody

Specificity: This antibody detects endogenous human, mouse, and rat c-Jun only when phosphorylated at serine 79.

Cross-Reactivity: Human, Mouse, Rat

Immunogen: Peptide sequence that includes phosphorylation site of Serine 79 (G-A-S(p)-L-K) derived from human c-Jun and conjugated to KLH.

Application Details

Application Notes: Immunohistochemistry: use at dilution of 1:50- 1:100.
Immunofluorescence: use at dilution of 1:100- 1:200.
These are recommended working dilutions.
End user should determine optimal dilutions for their applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2 and Ca2 ), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: This antibody is stable for at least one (1) year at -20°C.

Target Details for C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Alternative Name: c-Jun

Background: C-Jun in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the JNK pathway but has also a phosphorylation-independent function

Pathways: MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins