Bcl-2 antibody

Catalog No. ABIN7265810

The Rabbit Monoclonal anti-Bcl-2 antibody has been validated for WB, IHC and IP. It is suitable to detect Bcl-2 in samples from Human.

Quick Overview for Bcl-2 antibody (ABIN7265810)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Bcl-2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-Bcl-2 Antibody

Purpose: Bcl-2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Bcl-2.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: BCL2

Background: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],Bcl-2,PPP1R50,BCL2,Apoptosis,Apoptosis_Bcl 2 family,Apoptosis_Inhibition of Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Autophagy,Cancer,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,Invasion and Metastasis,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Neurodegenerative Diseases,Neuroscience,PI3K-Akt Signaling Pathway,Protein phosphorylation,Signal Transduction,Stem Cells,Tumor biomarkers,BCL2

Molecular Weight: 26kDa

Gene ID: 596

UniProt: P10415

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling