ROS1 antibody (AA 2100-2200)

Catalog No. ABIN7265974

This Rabbit Polyclonal antibody specifically detects ROS1 in WB. It exhibits reactivity toward Human.

Quick Overview for ROS1 antibody (AA 2100-2200) (ABIN7265974)

Target: ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ROS1 Antibody

Binding Specificity: AA 2100-2200

Purpose: ROS1 Rabbit pAb

Sequence: IGDFGLARDI YKNDYYRKRG EGLLPVRWMA PESLMDGIFT TQSDVWSFGI LIWEILTLGH QPYPAHSNLD VLNYVQTGGR LEPPRNCPDD LWNLMTQCWA Q

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 2100-2200 of human ROS1 (NP_002935.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ROS1

Target: ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

Alternative Name: ROS1

Background: This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.,ROS1,MCF3,ROS,c-ros-1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,ROS1

Molecular Weight: 263kDa

Gene ID: 6098

UniProt: P08922

Pathways: RTK Signaling