Cathepsin D antibody

Catalog No. ABIN7266149

The Rabbit Monoclonal anti-Cathepsin D antibody has been validated for WB and IHC. It is suitable to detect Cathepsin D in samples from Human.

Quick Overview for Cathepsin D antibody (ABIN7266149)

Target: Cathepsin D (CTSD)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cathepsin D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cathepsin D Antibody

Purpose: Cathepsin D Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Cathepsin D .

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cathepsin D

Target: Cathepsin D (CTSD)

Alternative Name: CTSD

Background: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015],CLN10;CPSD;HEL-S-130P;Cathepsin D;CTSD,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Invasion and Metastasis,Neuroscience,Signal Transduction,Ubiquitin,CTSD

Molecular Weight: 46kDa/28kDa

Gene ID: 1509

UniProt: P07339

Pathways: Peptide Hormone Metabolism