CDK5RAP2 antibody (AA 1744-1893)

Catalog No. ABIN7266236

The Rabbit Polyclonal anti-CDK5RAP2 antibody is suitable to detect CDK5RAP2 in samples from Human. It has been validated for WB.

Quick Overview for CDK5RAP2 antibody (AA 1744-1893) (ABIN7266236)

Target: CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5RAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDK5RAP2 Antibody

Binding Specificity: AA 1744-1893

Purpose: CDK5RAP2 Rabbit pAb

Sequence: GQRLLAEMDI QTQEAPSSTS QELGTKGPHP APLSKFVSSV STAKLTLEEA YRRLKLLWRV SLPEDGQCPL HCEQIGEMKA EVTKLHKKLF EQEKKLQNTM KLLQLSKRQE KVIFDQLVVT HKILRKARGN LELRPGGAHP GTCSPSRPGS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1744-1893 of human CDK5RAP2 (NP_060719.4).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDK5RAP2

Target: CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))

Alternative Name: CDK5RAP2

Background: This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.,CDK5RAP2,C48,Cep215,MCPH3,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Microtubules,Neuroscience,CDK5RAP2

Molecular Weight: 206kDa/210kDa/211kDa/215kDa

Gene ID: 55755

UniProt: Q96SN8

Pathways: M Phase, SARS-CoV-2 Protein Interactome