COL17A1 antibody

Catalog No. ABIN7266467

The Rabbit Monoclonal anti-COL17A1 antibody is suitable to detect COL17A1 in samples from Human. It has been validated for WB and IHC.

Quick Overview for COL17A1 antibody (ABIN7266467)

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This COL17A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-COL17A1 Antibody

Purpose: Collagen XVII/COL17A1 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Collagen XVII/COL17A1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COL17A1

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Alternative Name: COL17A1

Background: This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008],BA16H23.2, BP180, BPA-2, BPAG2, ERED, LAD-1,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Extracellular Matrix_Collagen,Signal Transduction,COL17A1

Molecular Weight: 130,180kDa

Gene ID: 1308

UniProt: Q9UMD9