COL17A1 antibody

Catalog No. ABIN7244681

Product Details anti-COL17A1 Antibody

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL17A1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human COL17A1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COL17A1

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Alternative Name: COL17A1 (COL17A1 Products)

Synonyms: col17a1 antibody, fk89a06 antibody, si:ch211-223p8.6 antibody, wu:fk89a06 antibody, COL17A1 antibody, BA16H23.2 antibody, BP180 antibody, BPA-2 antibody, BPAG2 antibody, LAD-1 antibody, Bpag antibody, Bpag2 antibody, collagen type XVII alpha 1 chain antibody, collagen, type XVII, alpha 1b antibody, collagen, type XVII, alpha 1 antibody, Col17a1 antibody, col17a1b antibody, COL17A1 antibody

Background: COL17A1 (Collagen Type XVII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL17A1 include Epidermolysis Bullosa, Junctional, Non-Herlitz Type and Epithelial Recurrent Erosion Dystrophy. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. An important paralog of this gene is COL6A1.This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.

UniProt: Q9UMD9