COL17A1 antibody (Chain alpha 1, Middle Region)

Catalog No. ABIN951629

The Rabbit Polyclonal anti-COL17A1 antibody is suitable to detect COL17A1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for COL17A1 antibody (Chain alpha 1, Middle Region) (ABIN951629)

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL17A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-COL17A1 Antibody

Binding Specificity: Chain alpha 1, Middle Region

Specificity: This antibody reacts to COL17A1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected between amino acids 490 and 520 of human COL17A1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for COL17A1

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Background: COL17A1 encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.Synonyms: 180 kDa bullous pemphigoid antigen 2, BP180, BPAG2, Bullous pemphigoid antigen 2, COL17A1, LABD97, LAD-1

Molecular Weight: 150419 Da

Gene ID: 1308

NCBI Accession: NP_000485